Formerly known as MOFAS: Minnesota Organization on Fetal Alcohol Syndrome

Exciting News
from MOFAS

If you're looking for the Minnesota Organization on Fetal Alcohol Syndrome (MOFAS) you have come to the right place. We have some exciting news about our organization. We have a new name! MOFAS has officially been renamed Proof Alliance. Our mission remains the same: to prevent prenatal alcohol exposure and to improve the quality of life for people living with fetal alcohol spectrum disorders (FASD).

Why PR%F

We now have the proof that prenatal alcohol exposure is a leading cause of brain injury in children. We have the proof that FASD is 100% preventable and people living with an FASD can reach 100% of their potential.

Why Alliance?

We seek to build powerful alliances with people with an FASD, their families, legislators, experts in the field, new partners, and community members to bring awareness, research, and services to this field.

What's Next?

Proof Alliance is rebranding, expanding, and we're moving! We have a new logo, website, and prevention campaign to help change the norms around drinking during pregnancy. And in May 2019 we will be moving to a stand-alone building. Proof Alliance commits to the people of Minnesota and we will continue to develop transformative programs to help Minnesotans impacted by FASD.

Is There a Safe Amount of Alcohol to Drink While I am Pregnant?

health care provider writing during exam with pregnant person

There is no known safe amount of alcohol during pregnancy.1 Even drinking at low levels can affect fetal development.2 This is because alcohol is a teratogen that crosses the placenta and can damage the central nervous system (including the brain) and other organs of the developing embryo/fetus.3 No more than two hours after maternal ingestion, the blood alcohol level of the fetus is the same as or higher than the mother’s.1

Harmful effects from prenatal alcohol exposure have been well-documented.4-6 This includes physical birth defects and brain-based disabilities.7-12 The risks posed to the fetus increase as maternal alcohol use rises.13 Overall, the scientific community continues to advise that the healthiest and safest choice is to abstain from alcohol during pregnancy – from conception through birth. 14-20

 Learn more about alcohol-free pregnancies.

Sources:

  1. Burd L, Blair J, Dropps K. Prenatal alcohol exposure, blood alcohol concentrations and alcohol elimination rates for the mother, fetus and newborn. Journal of Perinatology. 2012;32(9):652-659.
  2. Terasaki LS, Schwarz JM. Impact of Prenatal and Subsequent Adult Alcohol Exposure on Pro-Inflammatory Cytokine Expression in Brain Regions Necessary for Simple Recognition Memory. Brain Sciences (2076-3425). 2017;7(10):1-16.
  3. Fitzpatrick JP, Pestell CF. Neuropsychological Aspects of Prevention and Intervention for Fetal Alcohol Spectrum Disorders in Australia. Journal of Pediatric Neuropsychology. 2017;3(1):38-52.
  4. Treit et al. Longitudinal MRI reveals altered trajectory of brain development during childhood and adolescence in fetal alcohol spectrum disorders, Journal of Neuroscience. 2013;33(24):10098-109.
  5. Hendrickson et al. Cortical gyrification is abnormal in children with prenatal alcohol exposure, NeuroImage: Clinical. 2017;15:391-400.
  6. Popova S, et al. Comorbidity of Fetal Alcohol Spectrum Disorder: A Systematic Review and Meta-Analysis. The Lancet, 2016;387(10022):5-11.
  7. Feldman HS, et al. Prenatal Alcohol Exposure Patterns and Alcohol-Related Birth Defects and Growth Deficiencies: A Prospective Study. Alcohol Clin Exp Res. 2012;36(4):670-676.
  8. Treit S, Zhou D, Chudley AE, et al. Relationships between Head Circumference, Brain Volume and Cognition in Children with Prenatal Alcohol Exposure. PLoS ONE. 2016;11(2):1-15.
  9. Sawada Feldman H, Lyons Jones K, Lindsay S, et al. Prenatal Alcohol Exposure Patterns and Alcohol-Related Birth Defects and Growth Deficiencies: A Prospective Study. Alcoholism: Clinical & Experimental Research. 2012;36(4):670-676.
  10. Muralidharan P, Sarmah S, Feng C. Zhou, Marrs JA. Fetal Alcohol Spectrum Disorder (FASD) Associated Neural Defects: Complex Mechanisms and Potential Therapeutic Targets. Brain Sciences (2076-3425). 2013;3(2):964-991.
  11. Lewis SM, Vydrová RR, Leuthold AC, Georgopoulos AP. Cortical miscommunication after prenatal exposure to alcohol. Experimental Brain Research. 2016;234(11):3347-3353.
  12. Girault V, et al. Prenatal Alcohol Exposure Impairs Autophagy in Neonatal Brain Cortical Microvessels. Cell Death & Disease. 2017; 8(e2610).
  13. May PA et al. Maternal alcohol consumption producing fetal alcohol spectrum disorders (FASD): quantity, frequency, and timing of drinking. Drug and Alcohol Dependence. 2013; 133(2): 502-512.
  14. Williams JF, Smith VC. Fetal Alcohol Spectrum Disorders. Pediatrics. 2015;136(5):e1395-406.
  15. O’Leary CM, Bower C. Guidelines for pregnancy: What’s an acceptable risk, and how is the evidence (finally) shaping up? Drug & Alcohol Review. 2012;31(2):170-183.
  16. Centers for Disease Control and Prevention. Fetal Alcohol Spectrum Disorders (FASDs). https://www.cdc.gov/ncbddd/fasd/alcohol-use.html
  17. American Academy of Pediatrics. AAP Says No Amount of Alcohol Should Be Considered Safe During Pregnancy. https://www.aap.org/en-us/about-the-aap/aap-press-room/Pages/AAP-Says-No-Amount-of-Alcohol-Should-be-Considered-Safe-During-Pregnancy.aspx
  18. Centers for Disease Control and Prevention. Notice to Readers: Surgeon General’s Advisory on Alcohol Use in Pregnancy. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5409a6.htm
  19. National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism. Fetal Alcohol Exposure. https://www.niaaa.nih.gov/alcohol-health/fetal-alcohol-exposure
  20. World Health Organization. Counting the Costs of Drinking Alcohol During Pregnancy. https://www.who.int/bulletin/volumes/95/5/17-030517/en/

Last updated: March 2019

 

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